Assoc. Prof. Kylie MansfieldAssociate Professor Kylie Mansfield

Director of Curriculum

Associate Professor Kylie Mansfield is the Director of Curriculum at Graduate Medicine. She has a PhD in cellular physiology and academic experience teaching and facilitating students studying medicine and medical science as well as supervising and mentoring undergraduate and postgraduate research students. In 2011 Kylie led the Phase 1 team in obtaining a UOW award for Outstanding Contribution to Learning and Teaching award. In 2013 Kylie was awarded an Office of Learning and Teaching citation for “extraordinary attention to student and staff diversity that shapes leadership of the integrated Phase 1 medical curriculum at the University of Wollongong”.

In 2013, Kylie and Associate Professor Lyndal Parker-Newlyn (also from GM) developed a MOOC (Massive Open Online Course) with Open2Study (a subsidiary of Open Universities Australia) called “Understanding Common Diseases”. This course is run every 5 weeks on the Open2Study platform and is available to anyone who wants to learn more about their health and how the body works. The Understanding Common Diseases MOOC has been well received with up to 1000 people from Australia and around the world enrolling each time the course is run.

Kylie has diverse research experience in the fields of physiology and pharmacology based mainly around investigating the aetiology of overactive bladder. This disorder can lead to urinary incontinence, a debilitating chronic disease responsible for loss of social dignity, with major socio-economic costs. Because patients are reluctant to speak about this disorder it is not widely known that 17% of people over age 40 suffering from OAB symptoms. “Urge incontinence” occurs without warning, when muscular spasms arise in the wall of the bladder. The cause of such detrusor muscle spasms is not known. The main treatment is with antimuscarinic drugs, but associated side effects are often use limiting.

In the laboratory at IHMRI, UOW, Kylie together with Dr Jessica Hughes, is investigating the effect of inflammation on release of urothelial cell mediators. In particular they are investigating the factors that alter purinergic signalling in the bladder by measuring release of ATP from urothelial cells.

In 2014, together with Prof. Kate Moore (St George Hospital) and Prof. Val Gebski (Sydney University NHMRC clinical trials centre), Kylie was successful in obtaining funding from the BUPA health foundation for a randomised controlled trial of antibiotics in patients with refractory detrusor overactivity. This work is based on recent research conducted by this group showing that sub-clinical infection may be present in up to 30% of patients who are refractory to the usual antimuscarinic therapy. This trial is registered with the Australian clinical trials registry (ACTRN12613000285752), has received ethical approval and recruitment is currently underway.

Searchable select RIS publications from 2000 to date

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Phone: +61 2 4221 5851
Fax: +61 2 4221 4341
Office: B28.120
Last reviewed: 24 August, 2017