Dr Haibo Yu
Position: Senior Lecturer
Phone: +61 2 4221 4235
Downloadable Publications: ORCID, UOW Research Online
Yu Research Group - Computational Chemistry and Biophysics
The central theme of my research program can be summarized as developing and applying theoretical and computational tools to understand the structure-dynamics-function relationship in complex (bio)molecular and nanoscale systems. Complementary to experimental investigations, such studies can gain new physical insights into the underlying mechanism and provide necessary knowledge for manipulation in molecular engineering applications and discovery of novel therapeutics. Currently, the specific problems of interest include protein-DNA interactions, mechanistic studies of luciferases and carbohydrate-active enzymes and photolyases, drug design targeting protein tyrosine phosphatase 1B and urokinase-type plasminogen activator.